Four police were killed and nine other people wounded when militants detonated a bomb hidden under a motorbike in Quetta, police said on Monday.
The Pakistani Taliban claimed responsibility for the attack.
Two police were among the wounded, senior police official Abdul Razaq Cheema told AFP. “Two of the injured are critical,” he added.
The motorbike was parked outside a mosque where police personnel were posted in Quetta, the capital of Balochistan province.
Forensic investigators worked at the scene, placing evidence markers around a car, one door of which was open and partially shredded. What appeared to be a pool of blood stained the ground in front of the car.
The attack came two days after Baloch separatists attacked a luxury hotel in the province’s second city, Gwadar, where development of a port is the flagship project of a multi-billion dollar Chinese infrastructure initiative in Pakistan.
Five people including a soldier died in the hotel attack, which also left all three militants dead. The violence came during the Muslim holy fasting month of Ramzan.
Balochistan, Pakistan’s largest and poorest province, which borders Afghanistan and Iran, is rife with Islamist, separatist and sectarian insurgencies. The Pakistani military has been waging war on militants there since 2004, and security forces are frequently targeted.
Rights activists accuse the military of abuses, which it denies.
Balochistan is key to the China-Pakistan Economic Corridor (CPEC), part of Beijing’s Belt and Road initiative. CPEC seeks to connect China’s western province of Xinjiang with Gwadar, giving Beijing access to the Arabian Sea.